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HIV Hidden in Patients’ Cells Can Now Be Accurately Measured

A new genetic technique quantifies a latent form of the HIV virus, quickly and accurately.

Researchers can now quickly and accurately count a hidden, inactive form of the human immunodeficiency virus (HIV) that lurks in patients’ cells. This version of HIV embeds into cells’ genomes and can persist despite otherwise successful therapies – thwarting attempts to cure the infection.

Using a new genetic technique developed by Howard Hughes Medical Institute Investigator Robert Siliciano and colleagues, researchers will finally be able to measure just how much of this viral form is hiding in the body­ – a crucial part of evaluating the effectiveness of new treatments, Siliciano says.

"We may still be a long way from a cure, but now at least we can measure our progress."

Keep reading about this exciting research, reported in the journal Nature on January 30, 2019.

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